Endocrine Abstracts

Disturbed oestrogen homeostasis is associated with an increased risk of cardiovascular disease. However, the impact of dysregulated oestrogen signalling on vascular development, maintenance and disease is not fully understood. Zebrafish is a well-established model in translational vascular research. In addition, oestrogen receptor expression and oestrogen-responsiveness in endothelial cells (EC) is conserved in zebrafish. Therefore, the aim of this study was to characterise th...